Factors associated with satisfaction with social roles and activities among people with systemic sclerosis: a Scleroderma Patient-centered Intervention Network (SPIN) cohort cross-sectional study

                    Objective
                    The objectives were to (1) compare satisfaction with social roles
                        and activities in a large multinational systemic sclerosis (SSc) cohort
                        to general population normative data and (2) identify sociodemographic,
                        lifestyle and SSc disease factors associated with satisfaction with
                        social roles and activities.
                
                
                    Methods
                    Participants in the Scleroderma Patient-centered Intervention
                        Network Cohort completed the Patient Reported Outcomes Information
                        System Version 2 satisfaction with social roles and activities domain
                        questionnaire. Multivariable regression was used to assess associations
                        with sociodemographic, lifestyle and disease factors.
                
                
                    Results
                    Among 2385 participants, mean satisfaction with social roles and
                        activities T-score (48.1, SD=9.9) was slightly lower than the US general
                        population (mean=50, SD=10). Factors independently associated with
                        satisfaction were years of education (0.54 per SD, 95% CI 0.14 to 0.93);
                        non-White race or ethnicity (−1.13, 95% CI −2.18 to –0.08); living in
                        Canada (−1.33, 95% CI −2.40 to –0.26 (reference USA)) or the UK (−2.49,
                        95% CI −3.92 to –1.06); body mass index (−1.08 per SD, 95% CI −1.47 to
                        –0.69); gastrointestinal involvement (−3.16, 95% CI −4.27 to –2.05);
                        digital ulcers (−1.90, 95% CI −3.05 to –0.76); moderate (−1.62, 95% CI
                        −2.78 to –0.45) or severe (−2.26, 95% CI −3.99 to –0.52) small joint
                        contractures; interstitial lung disease (−1.11, 95% CI −1.97 to –0.25);
                        pulmonary arterial hypertension (−2.69, 95% CI −4.08 to –1.30);
                        rheumatoid arthritis (−2.51, 95% CI −4.28 to –0.73); and Sjogren’s
                        syndrome (−2.42, 95% CI −3.96 to –0.88).
                
                
                    Conclusion
                    Mean satisfaction with social roles and activities is slightly lower
                        in SSc than the general population and associated with multiple
                        sociodemographic and disease factors.